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Athira Scientific Publications and Presentations

SfN 2024

AAIC 2024

ENCALS 2024

ALS DDS 2024

AAN 2024

ASENT 2024

AD/PD 2024

ALS/MND 2023

SfN 2023

CTAD 2023

NEALS 2023

AAIC 2023

ALS DDS 2023

AAN 2023

AD/PDTM 2023

ASENT 2023

MNDA 2022

CTAD 2022

SfN 2022

AAIC 2022

PNS 2022

AD/PDTM 2022

AAIC 2021

ASENT 2022

CTAD 2021

CTAD  2019

PUBLICATIONS

Neurotherapeutics (Reda et al.)

Fosgonimeton attenuates amyloid-beta toxicity in preclinical models of Alzheimer’s disease

Frontiers in Neuroscience (Berthiaume, Reda at al.)

ATH-1105, a small-molecule positive modulator of the neurotrophic HGF system, is neuroprotective, preserves neuromotor function, and extends survival in preclinical models of ALS

Journal of Alzheimer’s Disease (Moebius and Church)

The Case for a Novel Therapeutic Approach to Dementia: Small Molecule Hepatocyte Growth Factor (HGF/MET) Positive Modulators

Neurotherapeutics (Johnston et al.)

Fosgonimeton, a Novel Positive Modulator of the HGF/MET System, Promotes Neurotrophic and Procognitive Effects in Models of Dementia

Neural Plasticity (Olichney et al.)

Predictive Power of Cognitive Biomarkers in Neurodegenerative Disease Drug Development: Utility of the P300 Event-Related Potential

Journal of Alzheimer’s Disease (Hua et al.)

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Positive Modulator of HGF/MET, Fosgonimeton, in Healthy Volunteers and Subjects with Alzheimer’s Disease: Randomized, Placebo-Controlled, Double-Blind, Phase I Clinical Trial